By Lucinda L. Veeck, Nikica Zaninovic
When you had a accountable technique for choosing the healthiest and so much doable conceptus from a cohort of turning out to be preembryos, changing greater than a unmarried one that allows you to in attaining sturdy being pregnant premiums will be moot. someday within the not-so-distant destiny, this can be a truth. Taking a step in the direction of that destiny, An Atlas of Human Blastocysts vividly illustrates the common and ordinary morphology of mammalian blastocysts. The atlas demonstrates that prolonged tradition of blastocysts is now feasible within the laboratory and issues us towards the day whilst will probably be attainable to select from a few fit hatched blastocysts.
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Additional resources for An atlas of human blastocysts
A retrospective analysis of unfertilized and presumed parthenogentically activated human oocytes demonstrates a high frequency of sperm penetration. Hum Reprod 1994; 9:2381–8 5. Edwards RG. Fertilization. In Edwards RG, ed. Conception in the Human Female. New York: Academic Press, 1980:604 (zona reaction), 617 (male pronucleus) 6. Dekel N, Beers WH. Development of the rat oocyte in vitro: inhibition and induction of maturation in the presence or absence of the cumulus oophorus. Dev Biol 1980; 75:247–54 7.
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Under suboptimal culture conditions the embryo exhibits abnormal energy metabolism, or expressed another way the embryo undergoes metabolic transformation. It is proposed that the ability of a given embryo to regulate against such metabolic transformation is related to its ability to develop in culture and ultimately to develop into a viable fetus after transfer. Interestingly, metabolic transformation is not restricted to the cleavage-stage embryo, but is also manifest at the blastocyst stage too.