An Introduction to General Virology by Thomas M. Bell (Auth.)

By Thomas M. Bell (Auth.)

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Interference has been demonstrated in the intact animal, the chick embryo and tissue cultures. 7 When a large dose of influenza virus is given intracerebrally, either before or at the same time as WEE the mice show no signs of illness. This high degree of protection against WEE lasts for about 7 days after inoculation of the influenza and then it gradually wanes until full susceptibility is restored at about the 21st day. An example of interference by killed virus is the protection of mice with U-V inactivated ectromelia virus.

14. 15. 16. REFERENCES Fazekas de St. Groth, S. (1962) Advances in Virus Research, 9, 1. Fazekas de St. , Webster, R. G. (1963) /. Immunol. 90, 140. Jerne, N. , Avegno, P. (1956) /. Immunol. 76, 200. Lafferty, K. J. D. Thesis, Australian Nat. Univ. Canberra. Fazekas de St. , Lafferty, K. J. (1958) /. Hyg. 56, 415. Sawyer, W. , Lloyd, W. (1931) /. Exper. Med. 54, 533. Lennette, E. , Koprowski, H. (1944) /. Immunol. 49, 375. Kjellen, L. ges. Virusforch. 7, 307. Amer. Pub. Health Assoc. Committee.

Burke, D. C. (1959) Brit. Med. Bull. 15, 185. 12. Burke, D. C. (1961) Biochem. J. 78, 556. 13. , Cantell, K. (1962) Virology, 18, 145. 14. Wagner, R. R. (1961) Virology, 13, 323. 15. Ho, M. (1961) Proc. Soc. Exp. Biol. Med. 107, 639. 16. , Schonne, E. (1962) Virology, 16, 63. 17. , Enders, J. F. (1959) Virology, 9, 446. 18. Chany, C. (1960) Compt. Rend. Acad. Sei. 250, 3903. 19. Cantell, K. ges. Virusforch. 10, 510. 20. , Porterfield, J. , Baron, S. (1961) Virology, 14, 450. 21. Warburg, O. (1956) Science, 124, 267.

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