By James D. Burrington, Douglas S. Clark
content material: Biocatalysis and biomimetics : new thoughts for chemistry / James D. Burrington --
Biomedical technological know-how and expertise : the interdisciplinary problem / Paul B. Weisz --
Interdisciplinary demanding situations : regulate of angiogenesis / Judah Folkman and Paul B. Weisz --
Crystallography and site-directed mutagenesis of 2 isomerases / Thomas C. Alber, Robert C. Davenport, Jr., Gregory ok. Farber, D. Ann Giammona, Arthur M. Glasfeld, William D. Horrocks, Masaharu Kanaoka, Elias Lolis, Gregory A. Petsko, Dagmar Ringe, and Gerard Tiraby --
Computer-automated series assessment of peptides : software to the examine of snake venom toxicity / Gilles Klopman and Ruben E. Venegas --
software of simulation and conception to biocatalysis and biomimetics / Adel M. Naylor and William A. Goddard, III --
Enzymatic reactions in reversed micelles at low solubilized water concentrations / J.W. defend, H.D. Ferguson, K.K. Gleason, and T.A. Hatton --
Enzyme constitution and serve as in water-restricted environments : electron paramagnetic resonance experiences in natural solvents and opposite micelles / Douglas S. Clark, Louise Creagh, Paul Skerker, Mark Guinn, John Prausnitz, and Harvey Blanch --
Hydroxylation of C₂, C₃, and cyclo-C₆ hydrocarbons by means of manganese porphyrin and nonporphyrin catalysts / Richard H. Fish, Raymond H. Fong, Robert T. fee, John B. Vincent, and George Christou --
Biomimetic catalytic oxidation of lignin version compounds / Robert DiCosimo and Hsiao-Chiung Szabo --
Zeolite catalysts as enzyme mimics : towards silicon-based existence? / Norman Herron --
Immobilization of proteins and enzymes onto functionalized polypropylene surfaces by means of a gaseous plasma amendment process / R. Sipehia, J. Daka, A.S. Chawla, and T.M.S. Chang.
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S. Feingole, Fed. Proc. Laurent, A. Tengblad, L. Hook and U. Lindahl, Biochem. J. J. Linhardt, A. L. Cooney and R. Langer, J. Biol. Chem. 257, 7310-7313, 1982; J. Choay, M. Petitou, J. Lormeau, P. Sinay, B. Casu and G. Gatt, Biochem. Biophys. Res. Comm. A. van Boeckel, T. F. van Aelst, Tetrahedron Letters 29, 803-806, 1988; J. L. Bender and M. Komiyama, "Cyclodextrin Chemistry", Springer-Verlag, Berlin, 1978; W. L. D. D. McNicol, Eds. Academic Press, New York, 1984; K. Uekama, T. Fujinaga, F. Hirayama, M.
Ve r e p l a c e d G l u 165 by Asp i n the ES complex, u s i n g computer g r a p h i c s to p o s i t i o n the a s p a r t a t e s i d e chain. Ve then cranked the two s i d e - c h a i n t o r s i o n a n g l e s o f the new Asp 165 through a l l p o s s i b l e v a l u e s i n i n c r e m e n t s , k e e p i n g the r e s t o f the p r o t e i n f i x e d . At each p o i n t i n the t o r s i o n a n g l e s c a n , the i n t e r a c t i o n p o t e n t i a l energy between Asp 165 and the s u r r o u n d i n g p r o t e i n atoms was computed.
S u p e r f i c i a l l y , t h i s d i f f e r e n c e may d i s c o u r a g e the thought of mutual i n t e r a c t i o n . However, an o l i g o m e r i c c h a i n of g l u c o s e r i n g s , can and w i l l a t t a i n a s p i r a l ( h e l i c a l ) configuration, especially with polar substituents directed outward t o i n t e r a c t w i t h the aqueous medium. Such h e l i c a l c o n f i g u r a t i o n i s observed f o r heparin (18 19). I t o f f e r s an apolar, hydrocarbon-like region for hydrophobic i n t e r a c t i o n (14) w i t h i n the c o n f i g u r a t i o n a l loops.